Medications & Sun Sensitivity: Summer Skin Protection

Jeremy Goodie • July 16, 2025
0 minute read
skin protection for the summer

Summer is the perfect time to get outside, enjoy the sunshine and soak up some vitamin D. But if you’re taking certain medications, your skin might not be as sun-friendly as you’d expect. Many common prescriptions and over-the-counter drugs can increase your sensitivity to sunlight, leading to quicker sunburns, rashes or more severe skin reactions.


At St. Hope Pharmacy, we’re here to help you stay safe and enjoy summer with confidence.


What Is Photosensitivity?


Photosensitivity, or sun sensitivity, is a heightened reaction of the skin to UV rays, either from the sun or artificial sources like tanning beds. This reaction can be triggered or worsened by certain medications and usually falls into two categories:


  1. Phototoxic reactions – These occur when UV light activates a compound in the medication, damaging skin cells and leading to symptoms that resemble an exaggerated sunburn.

  2. Photoallergic reactions – These are less common and involve the immune system mistaking a medication-UV combination for a threat, resulting in a rash or allergic-like response.


Both types of reactions can happen quickly or after repeated sun exposure while taking some medications.


Common Medications That Can Cause Sun Sensitivity


Sun sensitivity isn’t limited to rare or complex prescriptions. In fact, many widely used medications come with this risk. Some of the most common include:


  • Antibiotics – Especially tetracyclines (like doxycycline), fluoroquinolones (like ciprofloxacin) and sulfa drugs
  • Antihistamines – Such as diphenhydramine (Benadryl)
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) – Like ibuprofen and naproxen
  • Diuretics – Often used for high blood pressure or heart conditions
  • Retinoids – Both oral and topical forms used for acne or anti-aging
  • Antidepressants and antipsychotics – Especially tricyclics and some SSRIs
  • Chemotherapy drugs
  • Antifungal medications


This list isn’t exhaustive, and the degree of sensitivity can vary. If you’re unsure whether your medication poses a risk, your pharmacist is a great resource.


Signs of a Photosensitive Reaction


If you’re taking a sun-sensitizing medication, it’s important to recognize the symptoms of a reaction early. Watch for:


  • Redness or severe sunburn, even after limited sun exposure
  • Itching, stinging or burning of the skin
  • Rash or hives that appear only on sun-exposed areas
  • Blistering or peeling in more extreme cases


These symptoms may show up within minutes to hours after sun exposure and can worsen with repeated exposure if the medication isn’t discontinued or sun protection precautions aren't taken.


How to Protect Yourself


The good news is that sun sensitivity doesn’t mean you have to stay indoors all summer. With a few practical steps, you can reduce your risk and enjoy the season safely:


1. Check with Your Pharmacist

Before starting a new medication, or if you’re unsure about an existing one, ask your pharmacist if it can increase sun sensitivity. At St. Hope Pharmacy, we’re always happy to review your medications and provide personalized advice.


2. Limit Sun Exposure

Try to avoid being in direct sunlight during peak UV hours (10 a.m. to 4 p.m.) if you’re using a medication that increases sun sensitivity. If you do go out, seek shade when possible and plan outdoor activities in the early morning or evening.


3. Wear Protective Clothing

Clothing is one of the most effective ways to block UV rays. Choose lightweight, long-sleeved shirts, wide-brimmed hats and sunglasses with UV protection. Some garments are labeled with UPF (Ultraviolet Protection Factor) for added assurance.


4. Use Broad-Spectrum Sunscreen

Choose a broad-spectrum sunscreen with SPF 30 or higher. Apply it generously 15–30 minutes before going outside, and reapply every two hours, or more often if swimming or sweating. Make sure to cover easily missed spots like your ears, neck and tops of your feet.


5. Avoid Tanning Beds

If your skin is already more sensitive to UV light, using tanning beds significantly increases your risk of burns and long-term skin damage. It’s best to avoid them altogether.


6. Watch for Early Warning Signs

If you notice any unusual skin changes, burning sensations or rashes after sun exposure, take them seriously, especially if you’re on medication known to cause photosensitivity. Move indoors and contact your doctor or pharmacist for guidance.


Don’t Stop Medications Without Guidance


If you believe a medication is causing a reaction, it may be tempting to stop taking it. However, always speak with your healthcare provider before making any changes to your prescription. There may be alternatives available or ways to adjust the dosage or timing.


In some cases, temporary sun avoidance during the course of a short-term medication may be all that’s needed.


Get Advice From Your Neighborhood Pharmacy in Bellaire, Conroe, Houston, Sugar Land and Dickinson


At St. Hope Pharmacy, we do more than fill prescriptions; we help protect your health in every season. Whether you need advice on managing sun sensitivity, recommendations for safe sunscreen products or guidance on medication side effects, we’re here to support you and your family.


Need help reviewing your medications or planning for summer travel? Visit us at St. Hope Pharmacy today. We’re committed to helping you enjoy a safe, healthy and sun-smart summer.